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CAS号 | 2235394-90-6 | 货号 | BCP45170 |
中文名 | SHP389 | ||
英文名 | SHP389 | ||
中文别名 | |||
英文别名 | SHP-389; SHP 389; | ||
SMILES | O=C1C2=C(C3=C(Cl)C(NC4CC4)=NC=C3)NN=C2N=C(N(CC5)CCC65[C@H](N)[C@H](C)OC6)N1C | ||
化学名称 | |||
分子式 | C23H29ClN8O2 | 分子量 | 484.98 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | SHP389 is an allosteric SHP2 Inhibitor with (SHP2 IC50 - 36 nM). SHP389 modulates MAPK signaling in vivo.SHP389 improved SHP2 biochemical and cellular potency in trend with increasing lipophilicity. |
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