首页   >  
Cell Cycle/DNA Damage
  • Wnt/Stem Cell
  >  
Casein Kinase
  >   Silmitasertib sodium
Silmitasertib sodium 结构式

Silmitasertib sodium

参考资料 仅供科学研究,不可用于个人用途。
货号 :BCP38774CAS号 :1309357-15-0纯度:98%
全国免运费!免费咨询:400-099-8200 或 手机联系:13472751340
即时询价 ×

* 必填项

请填妥以下表格,您将在一分钟内得到邮件机器人给你的报价。

Product name

 

* Applicant name

Catalog Number

 

* Institution/Company

* Email address

 

Phone number

Country

 

* Quantity Required

Remarks

Inquiry Online ×

* Required Fields.

Please complete the form below and we will contact you shortly.

Product name

 

* Applicant name

Catalog Number

 

* Institution/Company

* Email address

 

Phone number

Country

 

* Quantity Required

Remarks

Bulk Inquiry ×

* Required Fields.

Please complete the form below and we will contact you shortly.

Product name

 

* Applicant name

Catalog Number

 

* Institution/Company

* Email address

 

Phone number

Country

 

* Quantity Required

Remarks

  • 基本信息与产品描述
CAS号 1309357-15-0 货号 BCP38774
中文名 Silmitasertib sodium
英文名 Silmitasertib sodium
中文别名
英文别名 Silmitasertib sodium salt;CX-4945 sodium salt;CX4945 Sodium;
SMILES C1=CC(=CC(=C1)Cl)NC2=NC3=C(C=CC(=C3)C(=O)[O-])C4=C2C=CN=C4.[Na+]
化学名称
分子式 C19H11ClN3NaO2 分子量 371.75
纯度 98% 配送 惯例下常温包邮
产品描述 Silmitasertib Sodium is the sodium salt of silmitasertib, an orally bioavailable small-molecule inhibitor of CK2 with potential antineoplastic activity. Silmitasertib selectively binds to and inhibits the enzyme casein kinase II (CK2), which may lead to an inhibition of cellular proliferation. CK2, a protein kinase often overexpressed in a variety of cancer cell types, appears to be correlated with malignant transformation, tumor growth and survival. CK2 regulates a diverse array of pro-survival cellular processes including epidermal growth factor receptor (EGFR) signaling, PI3K/AKT/mTOR signaling, hedgehog (Hh) signaling, Hsp90 machinery, hypoxia, and interleukin (IL)-6 expression. CK2 also regulates the activity of XRCC1 and MDC1, two mediator/adaptor proteins that are essential for DNA repair.
  • 技术资料和支持
在购买和使用瀚香生物产品的过程中,您遇到的任何问题,都可以咨询我们的免费热线:400-099-8200,或者和我们的客服 。 我们竭诚解决您的一切疑惑,保证您的舒心顺畅。

相关产品推荐

查看更多 >

Tags:Silmitasertib sodium 供应商,Silmitasertib sodium 购买,Silmitasertib sodium 生产,Silmitasertib sodium 批量,Silmitasertib sodium 供应,Silmitasertib sodium 订购,Silmitasertib sodium 采购

2853530910