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Emodin 结构式

大黄素

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货号 :BCP18372CAS号 :518-82-1纯度:98%
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  • 基本信息与产品描述
CAS号 518-82-1 货号 BCP18372
中文名 大黄素
英文名 Emodin
中文别名
英文别名 Emodol;Frangula emodin;
SMILES
化学名称
分子式 C15H10O5 分子量 270.24
纯度 98% 配送 惯例下常温包邮
产品描述 Emodin is a naturally-occurring anthraquinone found in a variety of plants used in traditional Chinese medicine. Purified emodin has diverse effects, including the suppression of inflammation, dyslipidemia, and cancer. At a molecular level, emodin directly and selectively inhibits casein kinase II (IC50 = 0.89 μM). Through this action, it inhibits the COP9 signalosome, causing the stabilization of the tumor suppressor p53. Moreover, emodin acts as a phytoestrogen, binding human estrogen receptors and blocking 17β-estradiol binding with Ki values of 0.77 and 1.5 μM for ERα and ERβ, respectively.
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