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CAS号 | 905105-89-7 | 货号 | BCP27716 |
中文名 | TMCB | ||
英文名 | TMCB | ||
中文别名 | |||
英文别名 | |||
SMILES | CN(C)C1=NC2=C(N1CC(=O)O)C(=C(C(=C2Br)Br)Br)Br | ||
化学名称 | |||
分子式 | C11H9Br4N3O2 | 分子量 | 534.83 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | TMCB is a dual-kinase inhibitor of both casein kinase 2 (CK2) and extracellular-signal-regulated kinase 8 (ERK8) (IC50 = 0.50 μM for both CK2 and ERK8). TMCB exhibits selectivity for CK2 over protein kinases normally susceptible to CK2 inhibitors (Ki = 0.25, 8.65, 11.90 and 15.25 μM for CK2, PIM1, DYRK1a and HIPK2, respectively). |
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