司曲替尼
CAS号 | 1123837-84-2 | 货号 | BCP29099 |
中文名 | 司曲替尼 | ||
英文名 | Sitravatinib | ||
中文别名 | |||
英文别名 | MGCD516; MGCD-516; MGCD 516; MG516; MG 516; MG-516; | ||
分子式 | C33H29F2N5O4S | 分子量 | 629.68 |
生物活性 | Sitravatinib, also known as MGCD516 or MG516, is a novel small molecule inhibitor targeting multiple RTKs involved in driving sarcoma cell growth. MGCD516 treatment resulted in significant blockade of phosphorylation of potential driver RTKs and induced potent anti-proliferative effects in vitro. MGCD516 treatment of tumor xenografts in vivo resulted in significant suppression of tumor growth. | ||
信号通路 | Angiogenesis/Protein Tyrosine Kinase | ||
靶 点 | TAM Receptor PDGFR c Met c Kit DDR |
结构式
本页面部分数据来自于公开的网络资源,所以瀚香生物不能保证其准确性。
不同批次的产品详情请咨询我们的客服:
- 全国免费电话:400-099-8200
瀚香生物(Biochempartner) 的所有产品和服务仅用于科学研究,禁止用于人体和治疗!