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CAS号 | 58131-57-0 | 货号 | BCP23434 |
中文名 | NSC-207895 | ||
英文名 | NSC-207895 | ||
中文别名 | |||
英文别名 | XI-006;XI 006;XI006;NSC 207895;NSC207895; | ||
SMILES | |||
化学名称 | |||
分子式 | C11H13N5O4 | 分子量 | 279.25 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | NSC207895 is a cell-permeable benzofuroxan compound that downregulates the p53 negative regulator MDMX protein level in MCF-7, LNCaP, and A549 cells (1 to 10 µM for 16 to 24 h) by suppressesing MDMX promoter transcription activity (IC50 = 2.5 µM in HT1080 cells), leading to enhanced p53 stabilization and activation. |
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