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CAS号 | 1364488-67-4 | 货号 | BCP09904 |
中文名 | YH239-EE | ||
英文名 | YH239-EE | ||
中文别名 | |||
英文别名 | YH239EE; | ||
SMILES | |||
化学名称 | |||
分子式 | C25H27Cl2N3O4 | 分子量 | 504.41 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | YH239-EE inhibits the growth of OCI-AML-3 cells with wild type p53 by inhibiting the p53-MDM2 interaction. YH239-EE induces cell cycle arrest and causes potent cell apoptosis via activation of p53 and downstream targets in four AML cells (OCI-AML-3 and MOLM-13 with wt p53, NB4 with p53 mutation, and HL60 with p53 deletion). |
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