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CAS号 | 1005264-47-0 | 货号 | BCP19296 |
中文名 | MX69 | ||
英文名 | MX69 | ||
中文别名 | |||
英文别名 | MX-69;MX 69; | ||
SMILES | |||
化学名称 | |||
分子式 | C27H26N2O4S | 分子量 | 474.57 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | MX69 blocks the MDM2 protein-XIAP RNA interaction, leading to MDM2 degradation. MX69 shows minimal inhibitory effect on normal human hematopoiesis in vitro and is very well tolerated in animal models. MX69-induced MDM2 downregulation results not only in inhibition of XIAP expression, but also in activation of p53, which contributes to cancer cell apoptosis in vitro and inhibition of cancer cell proliferation in vivo. |
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