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Sparsentan 结构式

Sparsentan

参考资料 仅供科学研究,不可用于个人用途。
货号 :BCP23969CAS号 :254740-64-2纯度:98%
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  • 基本信息与产品描述
CAS号 254740-64-2 货号 BCP23969
中文名 Sparsentan
英文名 Sparsentan
中文别名
英文别名 RE-021; RE021; RE 021; PS-433540; PS 433540; DARA-a;
SMILES CCCCC1=NC2(CCCC2)C(=O)N1CC3=CC(=C(C=C3)C4=CC=CC=C4S(=O)(=O)NC5=NOC(=C5C)C)COCC
化学名称
分子式 C32H40N4O5S 分子量 592.75
纯度 98% 配送 惯例下常温包邮
产品描述 Sparsentan is a Dual angiotensin II and endothelin A receptor antagonist. Retrophin intends to develop RE-021 for orphan indications of severe kidney diseases including Focal Segmental Glomerulosclerosis (FSGS) as well as conduct proof-of-concept studies in resistant hypertension and diabetic nephropathy. RE-021, with its unique dual blockade of angiotensin and endothelin receptors, is expected to provide meaningful clinical benefits in mitigating proteinuria in indications where there are no approved therapies.
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