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CAS号 | 254740-64-2 | 货号 | BCP23969 |
中文名 | Sparsentan | ||
英文名 | Sparsentan | ||
中文别名 | |||
英文别名 | RE-021; RE021; RE 021; PS-433540; PS 433540; DARA-a; | ||
SMILES | CCCCC1=NC2(CCCC2)C(=O)N1CC3=CC(=C(C=C3)C4=CC=CC=C4S(=O)(=O)NC5=NOC(=C5C)C)COCC | ||
化学名称 | |||
分子式 | C32H40N4O5S | 分子量 | 592.75 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | Sparsentan is a Dual angiotensin II and endothelin A receptor antagonist. Retrophin intends to develop RE-021 for orphan indications of severe kidney diseases including Focal Segmental Glomerulosclerosis (FSGS) as well as conduct proof-of-concept studies in resistant hypertension and diabetic nephropathy. RE-021, with its unique dual blockade of angiotensin and endothelin receptors, is expected to provide meaningful clinical benefits in mitigating proteinuria in indications where there are no approved therapies. |
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