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CAS号 | 150725-87-4 | 货号 | BCP17756 |
中文名 | Ro 46-2005 | ||
英文名 | Ro 46-2005 | ||
中文别名 | |||
英文别名 | Ro 462005;Ro 46 2005; | ||
SMILES | |||
化学名称 | |||
分子式 | C23H27N3O6S | 分子量 | 473.54 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | Ro 46-2005 proves to be equipotent (IC50 200-500 nM) for inhibition of [125I]ET-1 binding on the two known ET receptor subtypes (ETA and ETB). Ro 46-2005 also inhibits the functional consequences of ET-1 stimulation: the ET-l-induced release of arachidonic acid from rat mesangial cells was inhibited with an IC50 of 1.8 μM. |
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