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CAS号 | 156161-89-6 | 货号 | BCP28133 |
中文名 | BQ-788 钠盐 | ||
英文名 | BQ-788 Sodium | ||
中文别名 | |||
英文别名 | BQ-788 sodium salt ;BQ788; BQ-788; BQ 788; | ||
SMILES | |||
化学名称 | |||
分子式 | C34H50N5O7.Na | 分子量 | 663.79 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | BQ-788 (sodium salt) is a potent, selective ETB receptor antagonist with IC50 of 1.2 nM for inhibition of ET-1 binding to human Girardi heart cells, poorly inhibiting the binding to ETA receptors in human neuroblastoma cell line SK-N-MC cells with IC50 of 1300 nM.BQ788 is a endothelin B receptor antagonist. BQ788 attenuates stab wound injury-induced reactive astrocytes in rat brain. BQ788 were well tolerated and showed signs of directly and indirectly reducing the viability of melanoma cells. |
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