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CAS号 | 177036-94-1 | 货号 | BCP22426 |
中文名 | 安倍生坦 | ||
英文名 | Ambrisentan | ||
中文别名 | 2-(4,6-二甲基嘧啶-2-基)氧基-3-甲氧基-3,3-二苯基丙酸; | ||
英文别名 | BSF-208075; BSF208075; BSF 208075; LU-208075; LU208075; LU 208075; | ||
SMILES | |||
化学名称 | |||
分子式 | C22H22N2O4 | 分子量 | 378.43 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | Ambrisentan, also known as BSF-208075 and LU-208075, is a drug indicated for use in the treatment of pulmonary hypertension. Ambrisentan, which relaxes those muscles, is an endothelin receptor antagonist, and is selective for the type A endothelin receptor (ETA). Ambrisentan significantly improved exercise capacity (6-minute walk distance) compared with placebo in two double-blind, multicenter trials (ARIES-1 and ARIES-2). Ambrisentan was approved by the U.S. Food and Drug Administration (FDA) and European Medicines Agency, and designated an orphan drug, for the treatment of pulmonary hypertension. |
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