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CAS号 | 251356-45-3 | 货号 | BCP46277 |
中文名 | SU16F | ||
英文名 | SU16F | ||
中文别名 | |||
英文别名 | SU 16F;SU-16F; | ||
SMILES | CC1=C(NC(=C1CCC(=O)O)C)C=C2C3=C(C=C(C=C3)C4=CC=CC=C4)NC2=O | ||
化学名称 | |||
分子式 | C24H22N2O3 | 分子量 | 386.44 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | SU16F is a potent and selective PDGFRβ inhibitor with IC50s of 10 nM, 140 nM, 2.29 μM for PDGFRβ, PDGFR1, PDGFR2, respectively. Neutralization of PDGFRβ receptor by SU16f blocks the promoting role of GC-MSCs (gastric cancer-derived mesenchymal stem cells) conditioned medium in gastric cancer cell proliferation and migration. |
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