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CAS号 | 1018069-81-2 | 货号 | BCP25254 |
中文名 | TG 100801 Hydrochloride | ||
英文名 | TG 100801 Hydrochloride | ||
中文别名 | |||
英文别名 | TG-100801 Hydrochloride;TG100801 Hydrochloride; | ||
SMILES | |||
化学名称 | |||
分子式 | C33H31Cl2N5O3 | 分子量 | 616.54 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | TG 100801 Hydrochloride is a prodrug that generates TG 100572 by de-esterification in development to treat age-related macular degeneration. TG 100572 is a multi-targeted kinase inhibitor which inhibits receptor tyrosine kinases and Src kinases; has IC50s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.1, 0.4, 1, 0.2 for VEGFR1, VEGFR2, FGFR1, FGFR2, PDGFRβ, Fgr, Fyn, Hck, Lck, Lyn, Src, Yes, respectively. |
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