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Edicotinib

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货号 ：BCP25086CAS号 ：1142363-52-7纯度：98%
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  • 基本信息与产品描述
CAS号 1142363-52-7 货号 BCP25086
中文名 Edicotinib
英文名 Edicotinib
中文别名
英文别名 JNJ40346527; JNJ 40346527; JNJ-40346527;
SMILES
化学名称
分子式 C27H35N5O2 分子量 461.61
纯度 98% 配送 惯例下常温包邮
产品描述 Edicotinib, also known as JNJ-40346527, is a small molecule and orally available inhibitor of colony-stimulating factor-1 receptor (CSF1R; FMS) with potential antineoplastic activity. FMS tyrosine kinase inhibitor JNJ-40346527 blocks the receptor-ligand interaction between FMS and its ligand CSF1, thereby preventing autophosphorylation of FMS. As a result, unphosphorylated FMS cannot activate FMS-mediated signaling pathways, thus potentially inhibiting cell proliferation in FMS-overexpressed tumor cells.
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