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CAS号 | 1443530-05-9 | 货号 | BCP25142 |
中文名 | 罗加替尼 | ||
英文名 | Rogaratinib | ||
中文别名 | |||
英文别名 | BAY1163877; BAY-1163877; BAY 1163877; | ||
SMILES | CC1=CC2=C(C(=C1)OC)SC(=C2)C3=C4C(=NC=NN4C(=C3COC)CN5CCNC(=O)C5)N | ||
化学名称 | |||
分子式 | C23H26N6O3S | 分子量 | 466.56 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | Rogaratinib, also known as BAY-1163877, is an aberrant fibroblast growth factor receptor (FGFR) inhibitor. Rogaratinib is as an orally available, selective and potent inhibitor of FGFR-1, -2 and -3 kinase activity. FGFRs are a family of receptor tyrosine kinases, which may be upregulated in various tumor cell types and may be involved in tumor cell differentiation and proliferation, tumor angiogenesis, and tumor cell survival. |
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