首页   >  
MAPK Pathway
  >  
Raf
  >   PF-04880594
PF-04880594 结构式

PF-04880594

参考资料 仅供科学研究,不可用于个人用途。
货号 :BCP21016CAS号 :1111636-35-1纯度:98%
全国免运费!免费咨询:400-099-8200 或 手机联系:13472751340
即时询价 ×

* 必填项

请填妥以下表格,您将在一分钟内得到邮件机器人给你的报价。

Product name

 

* Applicant name

Catalog Number

 

* Institution/Company

* Email address

 

Phone number

Country

 

* Quantity Required

Remarks

Inquiry Online ×

* Required Fields.

Please complete the form below and we will contact you shortly.

Product name

 

* Applicant name

Catalog Number

 

* Institution/Company

* Email address

 

Phone number

Country

 

* Quantity Required

Remarks

Bulk Inquiry ×

* Required Fields.

Please complete the form below and we will contact you shortly.

Product name

 

* Applicant name

Catalog Number

 

* Institution/Company

* Email address

 

Phone number

Country

 

* Quantity Required

Remarks

  • 基本信息与产品描述
CAS号 1111636-35-1 货号 BCP21016
中文名 PF-04880594
英文名 PF-04880594
中文别名
英文别名 PF04880594; PF 04880594;
SMILES N#CCCNC1=NC=CC(C2=CN(CC(F)F)N=C2C3=CN=C(NC=C4)C4=C3)=N1
化学名称
分子式 C19H16F2N8 分子量 394.38
纯度 98% 配送 惯例下常温包邮
产品描述 PF-04880594 is a RAF inhibitor, which induces ERK phosphorylation and RAF dimerization in those epithelial tissues that undergo hyperplasia. PF-04880594 stimulates production of the inflammatory cytokine interleukin 8 in HL-60 cells. Epithelial tissue hyperplasia induced by the RAF inhibitor PF-04880594 is attenuated by a clinically well-tolerated dose of the MEK inhibitor PD-0325901. The combination treatment with PF-04880594 and MEK inhibitors might greatly increase the safety and therapeutic index of RAF inhibitors for the treatment of melanoma and other cancers.
  • 技术资料和支持
在购买和使用瀚香生物产品的过程中,您遇到的任何问题,都可以咨询我们的免费热线:400-099-8200,或者和我们的客服 。 我们竭诚解决您的一切疑惑,保证您的舒心顺畅。

相关产品推荐

查看更多 >

Tags:PF-04880594 供应商,PF-04880594 购买,PF-04880594 生产,PF-04880594 批量,PF-04880594 供应,PF-04880594 订购,PF-04880594 采购

2853530910