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CAS号 | 1715025-32-3 | 货号 | BCP38204 |
中文名 | Rineterkib | ||
英文名 | Rineterkib | ||
中文别名 | |||
英文别名 | ERK-IN-1; ERK IN 1; ERK IN-1; ERK-IN 1; | ||
SMILES | CNCC(C1=CC(=CC(=C1)Br)F)NC(=O)C2=C(C=C(C=C2)C3=NC(=CN=C3N)C4CCC(C(C4)F)O)F | ||
化学名称 | |||
分子式 | C26H27BrF3N5O2 | 分子量 | 578.4 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | Rineterkib is a RAF and ERK1/2 inhibitor in the treatment of a proliferative disease characterized by activating mutations in the MAPK pathway. The activity is particularly related to the treatment of KRAS-mutant NSCLC (non-small celllung cancer), BRAF-mutant NSCLC, KRAS-mutant pancreatic cancer, KRAS-mutant colorectal cancer (CRC) and KRAS-mutant ovanan cancer. |
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