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CUDC-101 结构式

CUDC-101

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货号 :BCP01935CAS号 :1012054-59-9纯度:98%
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  • 基本信息与产品描述
CAS号 1012054-59-9 货号 BCP01935
中文名 CUDC-101
英文名 CUDC-101
中文别名
英文别名 CUDC101;CUDC 101;
SMILES COC1=C(C=C2C(=C1)N=CN=C2NC3=CC=CC(=C3)C#C)OCCCCCCC(=O)NO
化学名称
分子式 C24H26N4O4 分子量 434.49
纯度 98% 配送 惯例下常温包邮
产品描述 CUDC-101 is a multi-targeted, small-molecule inhibitor of histone deacetylase (HDAC), epidermal growth factor receptor tyrosine kinase (EGFR/ErbB1), and human epidermal growth factor receptor 2 tyrosine kinase (HER2/neu or ErbB2) with potential antineoplastic activity. HDAC/EGFR/HER2 inhibitor CUDC-101 inhibits the activity of these three enzymes but the exact mechanism of action is presently unknown. This agent may help overcome resistance to inhibition of EGFR and Her2 through a simultaneous, synergistic inhibition of EGFR, Her2, and HDAC.
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