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CAS号 | 1012054-59-9 | 货号 | BCP01935 |
中文名 | CUDC-101 | ||
英文名 | CUDC-101 | ||
中文别名 | |||
英文别名 | CUDC101;CUDC 101; | ||
SMILES | COC1=C(C=C2C(=C1)N=CN=C2NC3=CC=CC(=C3)C#C)OCCCCCCC(=O)NO | ||
化学名称 | |||
分子式 | C24H26N4O4 | 分子量 | 434.49 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | CUDC-101 is a multi-targeted, small-molecule inhibitor of histone deacetylase (HDAC), epidermal growth factor receptor tyrosine kinase (EGFR/ErbB1), and human epidermal growth factor receptor 2 tyrosine kinase (HER2/neu or ErbB2) with potential antineoplastic activity. HDAC/EGFR/HER2 inhibitor CUDC-101 inhibits the activity of these three enzymes but the exact mechanism of action is presently unknown. This agent may help overcome resistance to inhibition of EGFR and Her2 through a simultaneous, synergistic inhibition of EGFR, Her2, and HDAC. |
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