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Sodium Butyrate 结构式

丁酸钠

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货号 :BCP31813CAS号 :156-54-7纯度:98%
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  • 基本信息与产品描述
CAS号 156-54-7 货号 BCP31813
中文名 丁酸钠
英文名 Sodium Butyrate
中文别名 正丁酸钠;
英文别名 Butyric acid sodium salt;
SMILES CCCC(=O)[O-].[Na+]
化学名称
分子式 C4H7NaO2 分子量 110.09
纯度 98% 配送 惯例下常温包邮
产品描述 Sodium Butyrate is the sodium salt of butyrate with potential antineoplastic activity. Butyrate, a short chain fatty acid, competitively binds to the zinc sites of class I and II histone deacetylases (HDACs). This binding affects hyperacetylation of histones, resulting in a modified DNA conformation, which subsequently leads to the uncoiling or relaxing of chromatin. Enhanced accessibility of chromatin to transcription-regulatory complexes leads to increased transcriptional activation of various epigenetically suppressed genes. Butyrate, a HDAC inhibitor, induces cell cycle arrest in G1 or G2/M and also increases the expression of other genes and proteins involved in cellular differentiation and apoptotic signaling.
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