所有产品分类
所有产品
信号通路
- Angiogenesis/Protein Tyrosine Kinase
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GPCR/G Protein
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Protease/Metabolic Enzyme
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研究领域
- Metabolic Disease
- Neurological Disease
- Endocrinology
- Diabetes
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- Inflammation
- Infection
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天然产物
抗体
多肽
催化剂
杂质对照品
医药中间体
基础原料
Wnt
结构式 | 货号 | 产品名称 | CAS号 |
---|
BCP28623 | LP-922056 新 | 1365060-22-5 | |
LP-922056 is a Notum pectinacetylesterase inhibitor which activates wnt signalling. LP-922056 increases cortical bone thickness in a mouse model of bone growth.
|
BCP47152 | ABC99 新 | 2331255-53-7 | |
ABC99 is an irreversible, potent and selective inhibitor against the serine hydrolase activity of the Wnt-deacylating enzyme NOTUM (IC50 = 13 nM). ABC99 preserves Wnt3A signaling in the presence of NOTUM.
|
BCP46893 | Box5 新 | 881188-48-3 | |
Box5, a Wnt5a-derived N-butyloxycarbonyl hexapeptide (t-Boc-Met-Asp-Gly-Cys-Glu-Leu), acts as an Wnt5a antagonist, inhibits the basal migration and invasion of Wnt5a-expressing HTB63 melanoma cells, antagonizes the effects of Wnt5a on melanoma cell migration and invasion by directly inhibiting Wnt5a-induced PKC and Ca(2+) signaling.
|
BCP45530 | HLY78 新 | 854847-61-3 | |
HLY78 is an activator of the Wnt/β-catenin signaling pathway, which targets the DIX domain of Axin and potentiates the Axin-LRP6 association to promote Wnt signaling transduction.
|
BCP45452 | FIDAS-3 新 | 1266684-01-8 | |
FIDAS-3 is a stilbene derivative and is a potent Wnt inhibitor with an IC50 of 4.9 μM for methionine S-adenosyltransferase 2A (MAT2A).
|
BCP44837 | Dalosirvat 新 | 1360540-81-3 | |
Dalosirvat is a topical Wnt pathway activator for the treatment of androgenetic alopecia (AGA).
|
BCP43701 | FOXY-5 新 | 881188-51-8 | |
FOXY-5 is a Wnt5a peptide mimetic. It has been undergoing clinical trials for the treatment of prostate cancer, colorectal cancer, metastatic colon cancer, metastatic breast cancer, and metastatic prostate cancer.
|
BCP43695 | 硫酸类肝素 新 | 9050-30-0 | |
Heparan sulfate, a complex and linear polysaccharide, exists as part of glycoproteins named heparan sulfate proteoglycans, which are expressed abundantly on the cell surface and in the extracellular matrix.
|
BCP42884 | Adavivint HCl 新 | AdavivintHCl | |
Adavivint is a small-molecule inhibitor of the Wnt pathway which is being investigated as a potential disease modifying agent for the treatment of osteoarthritis of the knee.
|
BCP41115 | IWP-O1 新 | 2074607-48-8 | |
IWP-O1 is a potent porcupine inhibitor that blocks Wnt signaling in L-Wnt-STF cells with EC50 value of 80 pM. IWP-O1 can affect differentiation of hESC.
|