所有产品分类
所有产品
信号通路
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研究领域
- Metabolic Disease
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天然产物
抗体
多肽
催化剂
杂质对照品
医药中间体
基础原料
Proteasome
结构式 | 货号 | 产品名称 | CAS号 |
---|
BCP48122 | Z-LLY-FMK 新 | 133410-84-1 | |
Z-LLY-FMK is a cell-permeable, potent, irreversible inhibitor of calpain II (k2 = 28,900 M-1s-1). Also blocks cathepsin L activity (k2 = 680,000 M-1s-1).
|
BCP48034 | LXE408 新 | 1799330-15-6 | |
LXE408 is a Kinetoplastid-Selective Proteasome Inhibitor for the Treatment of Leishmaniases
|
BCP40190 | Calpain Inhibitor XII 新 | 181769-57-3 | |
Calpain Inhibitor XII is a cell-permeable, potent, selective, reversible, and active-site-directed inhibitor of calpain-1 with Ki of 19 nM.
|
BCP37629 | TCH-165 新 | 1446350-60-2 | |
TCH-165 is a small molecule modulator of proteasome assembly, which increases 20S levels and facilitates 20S-mediated protein degradation.
|
BCP28014 | 钙蛋白酶抑制剂I 新 | 110044-82-1 | |
MG-101 is a potent inhibitor of cysteine proteases which inhibits calpain I, calpain II, cathepsin B and cathepsin L with Kis of 190, 220, 150 and 500 pM, respectively.
|
BCP13082 | MarizoMib 新 | 437742-34-2 | |
Marizomib, also known as ML 858, NPI-0052 and Salinosporamide A, is a potent and selective 20S proteasome inhibitor from natural origin.
|
BCP13243 | 乳胞素 新 | 133343-34-7 | |
Lactacystin is a specific and an irreversible inhibitor of proteasome with IC50 value of 4.8 μM.
|
BCP28290 | (R)-MG-132 新 | 1211877-36-9 | |
(R)-MG 132 is a potent 20S proteasome inhibitor (IC50 = 0.22 nM). Exhibits cytostatic and cytotoxic effects in tumor cells in vitro.
|
BCP28597 | PI-1840 | 1401223-22-0 | |
PI-1840 is a potent and selective inhibitor for chymotrypsin-like (CT-L) (IC50 value = 27 ± 0.14 nM) over trypsin-like and peptidylglutamyl peptide hydrolyzing (IC50 values >100 μM) activities of the proteasome.
|
BCP16600 | 枸橼酸艾莎佐米 | 1239908-20-3 | |
MLN2238 rapidly hydrolyzes to MLN2238, which is a selective, orally bioavailable, second-generation proteasome inhibitor, inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome with an IC50 value of 3.4 nM (Ki of 0.93 nM), and also inhibits the caspase-like (β1) and trypsin-like (β2) proteolytic sites with IC50 of 31 and 3500 nM, respectively.
|