所有产品分类
所有产品
信号通路
- Angiogenesis/Protein Tyrosine Kinase
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GPCR/G Protein
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Neuro Signaling Pathway
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Protease/Metabolic Enzyme
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研究领域
- Metabolic Disease
- Neurological Disease
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- Diabetes
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天然产物
抗体
多肽
催化剂
杂质对照品
医药中间体
基础原料
Ras/Rho
结构式 | 货号 | 产品名称 | CAS号 |
---|
BCP49689 | KRAS G12D inhibitor 18 新 | 2922732-54-3 | |
KRAS G12D inhibitor 18 is a potent KRAS G12D inhibitor.
|
BCP49682 | Garsorasib 新 | 2559761-14-5 | |
Garsorasib is an effective KRAS G12C inhibitor (IC50 = 10 nM) and can be used in studies about cancer treatment.
|
BCP49669 | 泛KRAS抑制剂 新 | 2765082-12-8 | |
RMC-7977 is a reversible, tri-complex RAS inhibitor with broad spectrum activity for both mutant and wild-type (WT) KRAS, NRAS, and HRAS variants.
|
BCP49649 | BI-2493 新 | 2937344-16-4 | |
BI-2493 is a structural analogue of BI-2865 that was optimized for in vivo administration.
|
BCP49648 | RAS-IN-2 新 | 2765081-21-6 | |
RAS-IN-2 (RMC-6236) is a potent pan-KRAS inhibitor targeting activation-state KRAS for cancer-related studies.
|
BCP49602 | BI-0474 新 | 2750570-55-7 | |
BI-0474 is a potent KRASG12C inhibitor with an IC50 value of 7.0 nM for the GDP-KRAS::SOS1 protein-protein interaction. BI-0474 exhibits good anti-proliferative activity against NCI-H358 cells carrying the G12C mutation. BI-0474 also shows good anti-tumour activity in non-small cell lung cancer xenograft models.
|
BCP49601 | BI-2865 新 | 2937327-93-8 | |
BI-2865 is a pan-KRAS inhibitor. BI-2865 inhibited the proliferation of isogenic G12C, G12D or G12V mutant KRAS expressing BaF3 cells more potently than precursor 1 with a mean IC50 of roughly 140 nM.
|
BCP49226 | D3S-001 新 | D3S-001 | |
D3S-001 is a potent and highly differentiated KRAS G12C inhibitor, which demonstrates rapid and near complete target inhibition and strong anti-tumor activity in preclinical cell line and animal models.
|
BCP48911 | MLS000532223 新 | 16616-39-0 | |
MLS000532223 is a high affinity, selective inhibitor of Rho family GTPases. It prevents GTP binding to several GTPases. Small GTPases are key regulators of cellular activity .
|
BCP30799 | AMG 510 Racemate 新 | AMG510Racemate |