所有产品分类
所有产品
信号通路
- Angiogenesis/Protein Tyrosine Kinase
- Apoptosis Pathway
- Cell Cycle/DNA Damage
- Epigenetics
-
GPCR/G Protein
- Urotensin Receptor
- Melatonin Receptor
- Neurotensin Receptor
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- TGR5
- Cholecystokinin Receptor
- Adenylate Cyclase
- Somatostatin Receptor
- Oxytocin Receptor
- Bradykinin Receptor
- Guanylate Cyclase
- Melanocortin Receptor
- Imidazoline Receptor
- Neuropeptide Receptor
- PAR
- CRFR
- Sigma Receptor
- S1P Receptor
- GHSR
- PKA
- OX Receptor
- Adenosine Receptor
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- Prostaglandin Receptor
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- Leukotriene Receptor
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- mAChR
- P2 Receptor
- GPR
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- Smoothened/Smo
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- Opioid Receptor
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- CCR
- 5 HT Receptor/Serotonin Receptor
- Hormone Pathay
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- Microbiology/Virology
-
Neuro Signaling Pathway
- Imidazoline Receptor
- Monoamine Oxidase
- COMT
- Amyloid β
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- Beta secretase
- AChE
- SSRI
- CaMK
- P glycoprotein
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- Adrenergic Receptor
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- Dopamine Transporter
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- FAAH
- CGRP Receptor
- nAChR
- COX
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- mAChR
- NFκB
- PI3K/Akt/mTOR
-
Protease/Metabolic Enzyme
- COMT
- 11β HSD
- Carboxypeptidase
- ACC
- Xanthine Oxidase
- Pyruvate Kinase
- Mitochondrial Metabolism
- ALDH
- SCD
- Serine Protease
- MLR
- FTase
- CETP
- Neprilysin
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- Carbonic Anhydrase
- E1 E2 E3 Enzyme
- Elastase
- PAI1
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- Glucokinase
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- DGAT
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- Phosphatase
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- HSP
- Tryptophan Hydroxylase/TPH
- Factor Xa
- DPP
- Procollagen C Proteinase
- Integrase
- Phosphodiesterase/PDE
- Phospholipase
- LXR
- Proteasome
- Cytochrome P450
- TGF beta/Smad
- Wnt/Stem Cell
- Others Pathway
研究领域
- Metabolic Disease
- Neurological Disease
- Endocrinology
- Diabetes
- Cardiovascular Disease
- Immunology
- Allergy
- Inflammation
- Infection
- Cancer
天然产物
抗体
多肽
催化剂
杂质对照品
医药中间体
基础原料
Trk Receptor
结构式 | 货号 | 产品名称 | CAS号 |
---|
BCP44112 | AZD-7451 新 | 1079274-94-4 | |
AZD7451 is a tropomyosin receptor kinase (TRK) inhibitor with potential antineoplastic activity
|
BCP33760 | CH7057288 新 | 2095616-82-1 | |
CH7057288 is a potent and selective TRK inhibitor.
|
BCP33232 | ONO7475 新 | 1646839-59-9 | |
ONO-7475 is a potent and orally active Axl/Mer inhibitor. ONO-7475 targets and binds to both Axl and Mer, and prevents their activity.
|
BCP30585 | LOXO-101 HCl salt 新 | 1919868-83-9 | |
LOXO-101 is an orally available, tropomyosin receptor kinase (Trk) inhibitor, with potential antineoplastic activity.
|
BCP30220 | LOXO195 R racemic (R外消旋) 新 | 1350884-56-8 | |
(6RS)-LOXO-195 is a potent and selective Trk tyrosine kinase inhibitor.The R racemate of LOXO-195, a potent, selective, next-generation Trk tyrosine kinase inhibitor with IC50 of 0.6 nM and <2.5 nM for WT TrkA and WT TrKC, respectively.
|
BCP30219 | LOXO195 RS-isomer(异构体) 新 | 2097002-59-8 | |
The RS-isomer of LOXO-195, a potent, selective, next-generation Trk tyrosine kinase inhibitor with IC50 of 0.6 nM and <2.5 nM for WT TrkA and WT TrKC, respectively.
|
BCP30139 | LM22B-10 新 | 342777-54-2 | |
LM22B-10 is an activator of TrkB/TrkC neurotrophin receptor, and can induce TrkB, TrkC, AKT and ERK activation in vitro and in vivo.
|
BCP16228 | PD90780 新 | 77422-99-2 | |
PD90780 is a nonpeptide inhibitor of NGF binding to p75NTR (IC50 ~ 1 μM in CHO cells); binds NGF, not p75NTR.
|
BCP01916 | AZ-23 新 | 915720-21-7 | |
AZ-23 is a potent and selective tyrosine kinase (Trk) inhibitor having potential for therapeutic utility in neuroblastoma and multiple other cancers.
|
BCP29619 | PF-06273340 | 1402438-74-7 | |
PF-06273340 is a potent, selective, and peripherally restricted Pan-Trk Inhibitor with an excellent LipE profile (IC50 value: Trk-A = 6 nM; Trk-B = 4 nM; Trk-C = 3 nM).
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