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研究领域
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天然产物
抗体
多肽
催化剂
杂质对照品
医药中间体
基础原料
Metabolic Disease
结构式 | 货号 | 产品名称 | CAS号 |
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BCP06882 | S0859 | 1019331-10-2 | |
S0859, an N-cyanosulphonamide compound, reversibly inhibited NBC-mediated pH(i) recovery (K (i)=1.7 microM, full inhibition at approximately 30 microM). Na(+)-coupled HCO(3)(-) transporters (NBCs) mediate the transport of bicarbonate ions across cell membranes and are thus ubiquitous regulators of intracellular pH.
|
BCP06935 | JNJ1661010 | 681136-29-8 | |
JNJ-1661010 is a potent and selective FAAH inhibitor with IC50 of 10 nM (rat) and 12 nM (human), exhibits >100-fold selectivity for FAAH-1 when compared to FAAH-2.
|
BCP04160 | 盐酸吉西他滨 新 | 122111-03-9 | |
Gemcitabine HCl is a DNA synthesis inhibitor with IC50 of 50 nM, 40 nM, 18 nM and 12 nM in PANC1, MIAPaCa2, BxPC3 and Capan2 cells, respectively.
|
BCP01411 | 度骨化醇 新 | 54573-75-0 | |
Doxercalciferol is a synthetic analog of vitamin D.
|
BCP03735 | 沙丙蝶呤 新 | 62989-33-7 | |
Sapropterin is a Phenylalanine Hydroxylase Activator. The mechanism of action of sapropterin is as a Phenylalanine Hydroxylase Activator, and Breast Cancer Resistance Protein Inhibitor, and P-Glycoprotein Inhibitor.
|
BCP06831 | 阿加曲班 | 74863-84-6 | |
Argatroban is a direct, selective thrombin inhibitor.
|
BCP03736 | 罗氟司特 | 162401-32-3 | |
Roflumilast is a selective inhibitor of PDE4 with IC50 of 0.2-4.3 nM.
|
BCP03724 | 西洛他唑 | 73963-72-1 | |
Cilostazol(OPC 13013; OPC 21) is a potent inhibitor of PDE3A, the isoform of PDE 3 in the cardiovascular system (IC50=0.2 uM).
|
BCP02332 | UK 383367 | 348622-88-8 | |
UK-383367 (UK 383367) is a Potent and selective inhibitor of BMP-1 (procollagen C-proteinase; PCP) (IC50 = 44 nM).
|
BCP02961 | 盐酸瓦地那非三水合物 | 224785-90-4 | |
Vardenafil Hydrochloride Trihydrate (Vivanza) is a new type PDE inhibitor with IC50 of 0.7 and 180 nM for PDE5 and PDE1, respectively.
|