所有产品分类
所有产品
信号通路
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GPCR/G Protein
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Protease/Metabolic Enzyme
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研究领域
- Metabolic Disease
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天然产物
抗体
多肽
催化剂
杂质对照品
医药中间体
基础原料
Kinesin
结构式 | 货号 | 产品名称 | CAS号 |
---|
BCP46472 | Paprotrain 新 | 57046-73-8 | |
Paprotrain is a cell-permeable inhibitor of the kinesin MKLP-2, inhibits the ATPase activity of MKLP-2 with an IC50 of 1.35 μM and a Ki of 3.36 μM and shows a moderate inhibition activity on DYRK1A with an IC50 of 5.5 μM.
|
BCP27898 | CW069 新 | 1594094-64-0 | |
CW-069 is a novel and allosteric inhibitor of the microtubule motor protein HSET, it shows statistically significant selectivity over KSP.
|
BCP30541 | MK-0731 新 | 845256-65-7 | |
MK-0731 is a synthetic small molecule with potential antineoplastic activity.
|
BCP07430 | AZD4877 | 1176760-49-8 | |
AZD4877 is a synthetic kinesin spindle protein (KSP) inhibitor with potential antineoplastic activity.
|
BCP28395 | ARQ 621 | 1095253-39-6 | |
ARQ-621 is an allosteric, potent and selective inhibitor of Eg5, a microtubule-based ATPase motor protein involved in cell division.
|
BCP17179 | Dimethylenastron | 863774-58-7 | |
Dimethylenastron is an Eg5 inhibitor, which arrests cells with monopolar spindles to which all chromosomes attach in a syntelic manner.
|
BCP03745 | EMD 534085 | 858668-07-2 | |
EMD534085 is a kinesin inhibitor currently in clinical development.
|
BCP06757 | Monastrol | 329689-23-8 | |
Monastrol is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5 with an IC50 value of 14 μM.
|
BCP19385 | Monastrol | 254753-54-3 | |
Monastrol is a kinesin Eg5 inhibitor. Induction of apoptosis by monastrol is independent of the spindle checkpoint.
|
BCP02454 | SB-715992 | 587881-28-5 | |
Ispinesib (SB-715992, CK0238273) is a potent, specific and reversible inhibitor of kinesin spindle protein (KSP) with Ki app of 1.7 nM, no inhibition to CENP-E, RabK6, MCAK, MKLP1, KHC or Kif1A.
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