所有产品分类
所有产品
信号通路
- Angiogenesis/Protein Tyrosine Kinase
- Apoptosis Pathway
- Cell Cycle/DNA Damage
- Epigenetics
-
GPCR/G Protein
- Urotensin Receptor
- Melatonin Receptor
- Neurotensin Receptor
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- Imidazoline Receptor
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Neuro Signaling Pathway
- Imidazoline Receptor
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- nAChR
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-
Protease/Metabolic Enzyme
- COMT
- 11β HSD
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- E1 E2 E3 Enzyme
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- Integrase
- Phosphodiesterase/PDE
- Phospholipase
- LXR
- Proteasome
- Cytochrome P450
- TGF beta/Smad
- Wnt/Stem Cell
- Others Pathway
研究领域
- Metabolic Disease
- Neurological Disease
- Endocrinology
- Diabetes
- Cardiovascular Disease
- Immunology
- Allergy
- Inflammation
- Infection
- Cancer
天然产物
抗体
多肽
催化剂
杂质对照品
医药中间体
基础原料
CCR
结构式 | 货号 | 产品名称 | CAS号 |
---|
BCP48543 | AZD-5672 新 | 780750-65-4 | |
AZD-5672 is an orally active, potent, selective CCR5 antagonist. AZD-5672 shows moderate activity against the hERG ion channel. AZD5672 is used for the research of rheumatoid arthritis.
|
BCP48070 | K-11777 新 | 233277-99-1 | |
K-11777 is a potent, orally active and irreversible cysteine protease inhibitor. K777 is also a potent CYP3A4 inhibitor with an IC50 of 60 nM and a selective CCR4 antagonist featuring the potent chemotaxis inhibition. K777 irreversibly inhibits Cruzain, the major cysteine protease of Trypansoma cruzi, and cathepsins B and L. K777 is a broad-spectrum antiviral by targeting cathepsin-mediated cell entry. K777 inhibits SARS-CoV and EBOV pseudovirus entry with IC50 values of 0.68 nM and 0.87 nM, respectively.
|
BCP35107 | INCB3344 新 | 1262238-11-8 | |
INCB3344 is a potent, selective and orally bioavailable CCR2 antagonist with IC50 values of 5.1 nM (hCCR2) and 9.5 nM (mCCR2) in binding antagonism and 3.8 nM (hCCR2) and 7.8 nM (mCCR2) in antagonism of chemotaxis activity.
|
BCP45725 | CCR3 antagonist 1 新 | 879399-82-3 | |
CCR3 antagonist 1 is a potent antagonist of CCR3, used for the research of immunologic and inflammatory diseases.
|
BCP44858 | CCR3 Antagonist 新 | 275812-32-3 |
BCP44354 | AZD-4818 新 | 1003566-93-5 | |
AZD-4818 is a chemokine CCR1 antagonist that is used for the treatment of chronic obstructive pulmonary disease.
|
BCP39005 | Nifeviroc 新 | 934740-33-7 | |
Nifeviroc is a CCR5 antagonist potentially for treatment of inflammatory responses to HIV type-1 infection
|
BCP37891 | R243 新 | 688352-84-3 | |
R243 is an inhibitor of CCR8 signaling and chemotaxis.
|
BCP37344 | TAK-220 新 | 333994-00-6 | |
TAK-220 is an orally bioavailable small-molecule CCR5 antagonist
|
BCP37346 | TAK-220 Hydrochloride 新 | 674782-27-5 | |
TAK-220 is a selective and orally bioavailable CCR5 antagonist.
|