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CaSR

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CaSR

结构式 货号 产品名称 CAS号
Encaleret sulfate hydrate 结构式
 BCP49240 Encaleret sulfate hydrate ESH
Encaleret is an oral calcium-sensing receptor (CaSR) antagonist, for the treatment of osteoporosis.
Encaleret sulfate 结构式
 BCP49235 Encaleret sulfate 1214922-52-7
Encaleret is an oral calcium-sensing receptor (CaSR) antagonist, for the treatment of osteoporosis.
Etelcalcetide 结构式
 BCP25088 维考西肽 1262780-97-1
Etelcalcetide (AMG 416) is a synthetic peptide as an activator of the calcium sensing receptor (CaSR). Etelcalcetide is effective in lowering parathyroid hormone (PTH) concentrations in patients receiving dialysis with secondary hyperparathyroidism receiving hemodialysis.
TNCA 结构式
 BCP48482 环甲基色氨酸 42438-90-4
TNCA is a high-affinity CaSR ligand (CaSRL) with co-agonist activity.
Evocalcet 结构式
 BCP33803 伊万卡赛 870964-67-3
Evocalcet is an orally available calcium receptor (CaR) modulator, with potential calcimimetic activity. Upon administration, evocalcet allosterically binds to and inhibits the activity of CaR, thereby suppressing the production of serum parathyroid hormone (PTH) and prevents the PTH-mediated efflux of calcium from bone and normalizes calcium levels.
Etelcalcetide HCl 结构式
 BCP25093 维考西肽盐酸盐 1334237-71-6
Etelcalcetide, also known as AMG 416 and KAI-4169, is a D-amino peptide calcimimetic undergoing clinical evaluation for the treatment of secondary hyperparathyroidism for patients with chronic kidney disease (CKD) on hemodialysis.
Ronacaleret HCl 结构式
 BCP11469 Ronacaleret HCl 702686-96-2
Ronacaleret, also known as SB751689, is an orally-active calcium-sensing receptor (CaSR) antagonist that has the potential for therapeutic utility in the stimulation of PTH release, notably as a bone anabolic agent comparable to recombinant human PTH(1-34) (rhPTH(1-34)).
SB-423562 结构式
 BCP29936 SB-423562 351490-27-2
SB-423562 is a short-acting calcium-sensing receptor (CaR) antagonist.
Strontium chloride 结构式
 BCP28245 氯化锶 10025-70-4
Calcium sensing receptor (CaSR) agonist. Activates ERK1/2 signaling, intracellular calcium mobilization, and calcitonin secretion. Enhances osteogenic differentiation of mesenchymal stem cells.
Cinacalcet 结构式
 BCP07181 甲状旁腺激素;西那卡塞 226256-56-0
AMG 073 represents a new class of compounds for the treatment of hyperparathyroidism.
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