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Tideglusib 结构式

Tideglusib

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货号 :BCP06016CAS号 :865854-05-3纯度:98%
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  • 基本信息与产品描述
CAS号 865854-05-3 货号 BCP06016
中文名 Tideglusib
英文名 Tideglusib
中文别名
英文别名 NP-12;NP031112;NP 031112;NP-031112;
SMILES
化学名称
分子式 C19H14N2O2S 分子量 334.39
纯度 98% 配送 惯例下常温包邮
产品描述 Tideglusib irreversibly inhibits GSK-3, reduces tau phosphorylation, and prevents apoptotic death in human neuroblastoma cells and murineprimary neurons.Tideglusib (2.5 μM) inhibits glutamate-induced glial activation as evidenced by decreased TNF-α and COX-2 expression in rat primary astrocyte or microglial cultures. Tideglusib (2.5 μM) also exerts a potent neuroprotective effect on cortical neurons from glutamate-induced excitotoxicity as evidenced by significant reduction in the number of Annexin-V-positive cells in rat primary astrocyte or microglial cultures.
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