CHIR-99021盐酸盐
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仅供科学研究,不可用于个人用途。
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250.00 mg | ¥1250.00 | In-stock | 购买咨询 |
1.00 g | 询价 | In-stock | 购买咨询 |
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CAS号 | 1797989-42-4 | 货号 | BCP26126 |
中文名 | CHIR-99021盐酸盐 | ||
英文名 | CHIR-99021 HCl | ||
中文别名 | |||
英文别名 | CHIR-911; CHIR911; CHIR 911; CT- 99021; CT-99021; CT- 99021; CHIR-73911; CHIR73911; CHIR 73911; GSK 3 inhibitor XVI; GSK 3IXV; CHIR99021; CHIR 99021; | ||
SMILES | N#CC1=CC=C(NCCNC2=NC=C(C3=NC=C(C)N3)C(C4=CC=C(Cl)C=C4Cl)=N2)N=C1.[H]Cl | ||
化学名称 | |||
分子式 | C22H19Cl3N8 | 分子量 | 501.8 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | CHIR99021, also known as CT99021, is a glycogen synthase kinase 3β (GSK3β) inhibitor that has antiproliferative activity in vitro and in vivo. CHIR-99021 inhibits GSK-3 with IC50 at 7 nM. In a series of carcinoma cell lines, the IC50 of CHIR99021 for proliferation is about 10μM. CHIR99021 promotes self-renewal of mouse embryonic stem cells by modulation of protein-encoding gene and long intergenic non-coding RNA expression. |
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