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Delapril hydrochloride 结构式

盐酸地拉普利

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货号 :BCP14202CAS号 :83435-67-0纯度:98%
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  • 基本信息与产品描述
CAS号 83435-67-0 货号 BCP14202
中文名 盐酸地拉普利
英文名 Delapril hydrochloride
中文别名
英文别名 Delapril HCl;CV-3317;CV 3317;CV3317;
SMILES CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N(CC(=O)O)C2CC3=CC=CC=C3C2.Cl
化学名称
分子式 C26H32N2O5.HCl 分子量 489.01
纯度 98% 配送 惯例下常温包邮
产品描述 Delapril Hydrochloride is the hydrochloride salt of delapril, a lipophilic, non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. As a prodrug, delapril is converted to two active metabolites, delapril diacid and 5-hydroxy delapril diacid, which competitively bind to and inhibit ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the potent vasoconstrictive actions of angiotensin II and results in vasodilation. Delapril also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex, which leads to an increase in sodium excretion and subsequently increases water outflow.
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