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CAS号 | 82586-52-5 | 货号 | BCP21379 |
中文名 | 莫西普利盐酸盐 | ||
英文名 | Moexipril hydrochloride | ||
中文别名 | |||
英文别名 | Moexipril HCL; RS 10085; RS-10085; RS10085; SPM-925; SPM 925; SPM925; CI-925; CI 925; CI925; | ||
SMILES | CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2CC3=CC(=C(C=C3CC2C(=O)O)OC)OC.Cl | ||
化学名称 | |||
分子式 | C27H35ClN2O7 | 分子量 | 535.03 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | Moexipril Hydrochloride is the hydrochloride salt form of moexipril, a prodrug and non-sulfhydryl angiotensin converting enzyme (ACE) inhibitor with antihypertensive activity. Moexipril hydrochloride is hydrolized into its active form moexiprilat, which competitively inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the actions of the potent vasoconstrictor angiotensin II and leads to vasodilatation. It also prevents angiotensin II-induced aldosterone secretion by the adrenal cortex, thereby promoting diuresis and natriuresis. Moexipril hydrochloride also directly suppresses renin release. |
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