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Zofenopril 结构式

佐芬普利

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货号 :BCP09233CAS号 :81872-10-8纯度:98%
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  • 基本信息与产品描述
CAS号 81872-10-8 货号 BCP09233
中文名 佐芬普利
英文名 Zofenopril
中文别名
英文别名 Zofenoprilum;SQ 26900;SQ-26900;SQ26900;(4S)-1-[(2S)-3-(Benzoylsulfanyl)-2-methylpropanoyl]-4-(phenylsulfanyl)-L-proline;
SMILES CC(CSC(=O)C1=CC=CC=C1)C(=O)N2CC(CC2C(=O)O)SC3=CC=CC=C3
化学名称
分子式 C22H23NO4S2 分子量 429.56
纯度 98% 配送 惯例下常温包邮
产品描述 Zofenopril is a sulfhydryl angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. As a prodrug, zofenopril is hydrolyzed in vivo into its active form zofenoprilat. Zofenoprilat competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the potent vasoconstrictive actions of angiotensin II and results in vasodilation. Zofenoprilat also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex, which leads to an increase in sodium excretion and subsequently increases water outflow.
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