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CAS号 | 87679-71-8 | 货号 | BCP38331 |
中文名 | 群多普利 | ||
英文名 | Trandolaprilat | ||
中文别名 | 群多普利拉;多普利拉; | ||
英文别名 | Trandolaprilate;Trandolaprilatum; | ||
SMILES | CC(C(=O)N1C2CCCCC2CC1C(=O)O)NC(CCC3=CC=CC=C3)C(=O)O | ||
化学名称 | |||
分子式 | C22H30N2O5 | 分子量 | 402.48 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | Trandolaprilat is a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. Trandolaprilat competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the potent vasoconstrictive actions of angiotensin II and results in vasodilation. Trandolaprilat also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex, which leads to an increase in sodium excretion and subsequently increases water outflow. |
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