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CAS号 | 752240-01-0 | 货号 | BCP42876 |
关联产品 | 1137916-97-2(MK-0941 mesylate) | ||
中文名 | MK-0941 | ||
英文名 | MK-0941 | ||
中文别名 | |||
英文别名 | MK 0941; MK0941; | ||
SMILES | CCS(=O)(=O)C1=NC=C(C=C1)OC2=CC(=CC(=C2)C(=O)NC3=NN(C=C3)C)OC(C)CO | ||
化学名称 | |||
分子式 | C21H24N4O6S | 分子量 | 460.5 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | MK-0941 is a glucokinase activator with EC50 values of 0.24 and 0.065 µM at low (2.5 mM) and high (10 mM) concentrations of glucose, respectively. It increases insulin secretion from isolated rat islets of Langerhans and glucose uptake by hepatocytes in vitro. MK-0941 reduces blood glucose levels in high-fat diet-fed db/db mice and in high-fat diet-fed mice with diabetes induced by streptozotocin . |
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