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Bisantrene dihydrochloride 结构式

比生群二盐酸盐

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货号 :BCP46265CAS号 :71439-68-4纯度:98%
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  • 基本信息与产品描述
CAS号 71439-68-4 货号 BCP46265
关联产品 78186-34-2(比生群)
中文名 比生群二盐酸盐
英文名 Bisantrene dihydrochloride
中文别名
英文别名 Bisantrene HCl;CL-216942; CL216942; CL 216942;
SMILES C1CN=C(N1)NN=CC2=C3C=CC=CC3=C(C4=CC=CC=C42)C=NNC5=NCCN5.Cl.Cl
化学名称
分子式 C22H24Cl2N8 分子量 471.39
纯度 98% 配送 惯例下常温包邮
产品描述 Bisantrene is topoisomerase II poisons and DNA intercalators. It may be used as model compounds to study P-glycoprotein-mediated multiple drug resistance (MDR1). Bisantrene may be used as a Rac1 inhibitor. Bisantrene intercalates with and disrupts the configuration of DNA, resulting in DNA single-strand breaks, DNA-protein crosslinking, and inhibition of DNA replication. This agent is similar to doxorubicin in activity, but unlike doxorubicin, does not exhibit cardiotoxicity.
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