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CAS号 | 166833-80-3 | 货号 | BCP28487 |
中文名 | 诃子宁 | ||
英文名 | Chebulanin | ||
中文别名 | |||
英文别名 | Terminalic acid; | ||
SMILES | C1=C(C=C(C(=C1O)O)O)C(=O)OC2C3C(C(C(O2)CO)OC(=O)C(C4C(C(=O)OC5=C4C(=CC(=C5O)O)C(=O)O3)O)CC(=O)O)O | ||
化学名称 | |||
分子式 | C27H24O19 | 分子量 | 652.47 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | Chebulanin is a topoisomerase I inhibitor. Chebulanin inhibits the calcineurin pathway in C. neoformans.Chebulanin exhibits potent antifungal activity against various human pathogenic fungi with minimum inhibitory concentrations ranging from 0.25 to over 64 μg/ml. Chebulanin suppresses the expression of inflammatory mediators and prevents cartilage destruction and bone erosion in mice, therefore, chebulanin is a strong therapeutic alternative for the treatment of rheumatism arthritis.Chebulanin shows strong radical scavenging activity, good potency to chelate Fe2⁺ and good inhibition ability of lipid peroxidation. Chebulanin has apparent capacities of inhibiting the survival of MCF-7 human cancer cell line. |
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