即时询价 ×
* 必填项
请填妥以下表格,您将在一分钟内得到邮件机器人给你的报价。
Inquiry Online
×
* Required Fields.
Please complete the form below and we will contact you shortly.
Bulk Inquiry
×
* Required Fields.
Please complete the form below and we will contact you shortly.
CAS号 | 2062661-53-2 | 货号 | BCP44778 |
中文名 | Tovinontrine | ||
英文名 | Tovinontrine | ||
中文别名 | |||
英文别名 | IMR-687; IMR 687; IMR687; | ||
SMILES | CC1CN(CC1C2=CN3C(=CN=C3C4CCOCC4)C(=O)N2)CC5=NC=CC=N5 | ||
化学名称 | |||
分子式 | C21H26N6O2 | 分子量 | 394.47 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | Tovinontrine, also known as IMR-687, is a phosphodiesterase 9 (PDE9) inhibitor. IMR-687 increased cGMP and HbF in erythroid K562 and UT-7 cells and increased the percentage of HbF positive erythroid cells generated in vitro using a two-phase liquid culture of CD34+ progenitors from sickle cell blood or bone marrow. Oral daily dosing of IMR-687 in the Townes transgenic mouse SCD model, increased HbF and reduced red blood cell sickling, immune cell activation and microvascular stasis. |
相关产品推荐
查看更多 >Tags:Tovinontrine 供应商,Tovinontrine 购买,Tovinontrine 生产,Tovinontrine 批量,Tovinontrine 供应,Tovinontrine 订购,Tovinontrine 采购