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CAS号 | 37762-06-4 | 货号 | BCP38400 |
中文名 | 扎普司特 | ||
英文名 | Zaprinast | ||
中文别名 | 苯氮嘌呤酮; | ||
英文别名 | |||
SMILES | CCCOC1=CC=CC=C1C2=NC3=NNN=C3C(=O)N2 | ||
化学名称 | |||
分子式 | C13H13N5O2 | 分子量 | 271.27 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | Zaprinast is a cyclic-GMP phosphodiesterase inhibitor with selectivity for PDE6, 5, 11 and 9 (IC50 = 0.15, 0.76, 12.0 and 29.0 μM, respectively). C-GMP acts as a mediator of signal transduction that relaxes vascular smooth muscles and increases blood flow. Therefore zaprinast exhibits vasodilating, relaxant, and diuretic effects. Zaprinast also acts as a putative GPR35 agonist. |
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