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CAS号 | 1257051-63-0 | 货号 | BCP37557 |
中文名 | THPP-1 | ||
英文名 | THPP-1 | ||
中文别名 | |||
英文别名 | |||
SMILES | COCCOC1=NC(=NC2=C1CN(CC2)C(=O)C3=C4C=CC=CN4C=N3)C5=CN=C(C=C5)Cl | ||
化学名称 | |||
分子式 | C23H21ClN6O3 | 分子量 | 464.91 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | THPP-1, a SGC chemical probe, is a potent and orally bioavailable phosphodiesterase 10A (PDE10A) inhibitor, with Ki values of 1 nM and 1.3 nM for human and rat PDE10A, respectively. THPP-1 has excellent pharmacokinetic properties in preclinical species. |
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