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CAS号 | 2007975-22-4 | 货号 | BCP34050 |
中文名 | DSR-141562 | ||
英文名 | DSR-141562 | ||
中文别名 | |||
英文别名 | DSR141562;DSR 141562; | ||
SMILES | CN1C(=O)C2=CN=C(N2N=C1OCC3CCC(CC3)C(F)(F)F)C4CCOCC4 | ||
化学名称 | |||
分子式 | C19H25F3N4O3 | 分子量 | 414.42 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | DSR-141562 is a novel, orally active, and selective brain-penetrant phosphodiesterase 1 (PDE1) inhibitor. DSR-141562 shows preferential selectivity for human PDE1B with an IC50 of 43.9 nM, and the IC50 values for human PDE1A and 1C are 97.6 and 431.8 nM, respectively. DSR-141562 can be used for the study of positive symptoms, negative symptoms and cognitive impairments associated with schizophrenia. |
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