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EST64454 HCl 结构式

EST64454 HCl

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货号 :BCP43797CAS号 :1950569-11-5纯度:98%
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  • 基本信息与产品描述
CAS号 1950569-11-5 货号 BCP43797
中文名 EST64454 HCl
英文名 EST64454 HCl
中文别名
英文别名 EST64454 hydrochloride;EST 64454 HCl;EST-64454 HCl;
SMILES CC(=O)N1CCN(CC1)CCOCC2=NN(C=C2)C3=CC(=C(C=C3)F)F.Cl
化学名称
分子式 C18H23ClF2N4O2 分子量 400.85
纯度 98% 配送 惯例下常温包邮
产品描述 EST64454 is a Highly Soluble σ1 Receptor Antagonist Clinical Candidate for Pain Management. EST64454 shows an outstanding aqueous solubility, which together with its high permeability in Caco-2 cells will allow its classification as a BCS class I compound. It also shows high metabolic stability in all species, linked to an adequate pharmacokinetic profile in rodents, and antinociceptive properties in the capsaicin and partial sciatic nerve ligation models in mice.
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