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CAS号 | 224177-60-0 | 货号 | BCP27822 |
关联产品 | 147817-50-3(西拉美新) | ||
中文名 | 西拉美新盐酸盐 | ||
英文名 | Siramesine hydrochloride | ||
中文别名 | 盐酸西拉美新; | ||
英文别名 | Siramesine HCl; Lu 28-179;Lu-28-179;Lu 28-179 hydrochloride; | ||
SMILES | FC1=CC=C(N2C=C(CCCCN3CCC4(CC3)OCC5=CC=CC=C45)C6=C2C=CC=C6)C=C1.[H]Cl | ||
化学名称 | |||
分子式 | C30H32ClFN2O | 分子量 | 491.04 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | Siramesine, also known as Lu-28-179, is a potent sigma-2 receptor agonist. Siramesine triggers cell death through destabilisation of mitochondria, but not lysosomes. Siramesine is a lysosomotropic detergent that induces cytoprotective autophagosome accumulation. Siramesine involves lysosomal leakage and oxidative stress. |
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