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BD1063 结构式

BD1063

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货号 :BCP28878CAS号 :150208-28-9纯度:98%
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  • 基本信息与产品描述
CAS号 150208-28-9 货号 BCP28878
中文名 BD1063
英文名 BD1063
中文别名
英文别名 BD 1063; BD-1063;206996-13-6(2HCl);BD-1063 Dihydrochloride; BD1063 Dihydrochloride;BD 1063 2HCl;
SMILES CN1CCN(CCC2=CC=C(Cl)C(Cl)=C2)CC1
化学名称
分子式 C13H18Cl2N2 分子量 273.20
纯度 98% 配送 惯例下常温包邮
产品描述 BD1063 is a selective sigma receptor antagonist, with a reported binding affinity of Ki = 9 ± 1 nM for the sigma-1 receptor and more than 49 times selectivity over the sigma-2 receptor. Consistent with other reported sigma receptor antagonists, pretreating Swiss Webster mice with BD1063 significantly decreases the convulsivity and lethality of cocaine. In other animal studies, BD1063 blocks the effects of MDMA, and reduces alcohol intake in rodent models of alcoholism.
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