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SB202190 结构式

SB202190

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货号 :BCP00675CAS号 :152121-30-7纯度:98%
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  • 基本信息与产品描述
CAS号 152121-30-7 货号 BCP00675
中文名 SB202190
英文名 SB202190
中文别名
英文别名 SB 202190;SB-202190;FHPI;
SMILES C1=CC(=CC=C1C2=NC(=C(N2)C3=CC=NC=C3)C4=CC=C(C=C4)F)O
化学名称
分子式 C20H14N3OF 分子量 331.34
纯度 98% 配送 惯例下常温包邮
产品描述 SB 202190 significantly inhibits both basal and anti-Fas antibody-induced MAPKAPK 2 activity in a dose-dependent manner. SB202190 by itself is sufficient to induce cell death in Jurkat and HeLa cells through activation of CPP32-like caspases, which can be blocked by expression of bcl-2. SB202190-induced apoptosis is attenuated by p38β but augmented by p38α. SB 202190 strongly inhibits UVB induced COX-2 protein expression in HaCaT cells, and markedly inhibits UVB induced cox-2 mRNA.
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