SB202190
CAS号 | 152121-30-7 | 货号 | BCP00675 |
中文名 | SB202190 | ||
英文名 | SB202190 | ||
中文别名 | |||
英文别名 | SB 202190;SB-202190;FHPI; | ||
分子式 | C20H14N3OF | 分子量 | 331.34 |
生物活性 | SB 202190 significantly inhibits both basal and anti-Fas antibody-induced MAPKAPK 2 activity in a dose-dependent manner. SB202190 by itself is sufficient to induce cell death in Jurkat and HeLa cells through activation of CPP32-like caspases, which can be blocked by expression of bcl-2. SB202190-induced apoptosis is attenuated by p38β but augmented by p38α. SB 202190 strongly inhibits UVB induced COX-2 protein expression in HaCaT cells, and markedly inhibits UVB induced cox-2 mRNA. | ||
信号通路 | MAPK Pathway | ||
靶 点 | p38 MAPK |
结构式
本页面部分数据来自于公开的网络资源,所以瀚香生物不能保证其准确性。
不同批次的产品详情请咨询我们的客服:
- 全国免费电话:400-099-8200
瀚香生物(Biochempartner) 的所有产品和服务仅用于科学研究,禁止用于人体和治疗!