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AZD-7451 结构式

AZD-7451

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货号 :BCP44112CAS号 :1079274-94-4纯度:98%
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  • 基本信息与产品描述
CAS号 1079274-94-4 货号 BCP44112
中文名 AZD-7451
英文名 AZD-7451
中文别名
英文别名 AZD7451; AZD 7451; AZ12607092; AZ 12607092; AZ-12607092;
SMILES CC(C)OC1=NNC(=C1)N2C=NC3=C2N=C(C=C3)NC(C)C4=NC=C(C=N4)F
化学名称
分子式 C18H19FN8O 分子量 382.39
纯度 98% 配送 惯例下常温包邮
产品描述 AZD7451 is a tropomyosin receptor kinase (TRK) inhibitor with potential antineoplastic activity. AZD7451 binds to TRK, thereby preventing the neurotrophin-TRK interaction and subsequent TRK activation. This may eventually result in an inhibition of tumor cell proliferation in TRK-expressing tumor cells. TRK, a receptor tyrosine kinase activated by neurotrophins, is mutated in a variety of cancer cell types and plays an important role in tumor cell growth, invasion and survival.
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