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CAS号 | 958295-17-5 | 货号 | BCP46996 |
中文名 | AGN 196996 | ||
英文名 | AGN 196996 | ||
中文别名 | |||
英文别名 | AGN-196996;AGN196996; | ||
SMILES | CCOC1=C(C=C(C=C1Br)C(=O)NC2=CC=C(C=C2)C(=O)O)C(=O)C3=CC=C(C=C3)C | ||
化学名称 | |||
分子式 | C24H20BrNO5 | 分子量 | 482.32 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | AGN 196996 is a potent and selective RARα antagonist with Ki value of 2 nM; little binding affinity for RARβ(Ki=1087 nM) and RARγ(Ki=8523 nM). IC50 value: 2 nM(Ki) Target: RARα antagonist AGN 196996 shows no activity in transactivation assays, but instead block the gene transcriptional activity induced by ATRA and other RAR agonists. |
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