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CAS号 | 153559-76-3 | 货号 | BCP08283 |
中文名 | LG100268 | ||
英文名 | LG100268 | ||
中文别名 | |||
英文别名 | LG 100268 ; LG-100268; | ||
SMILES | CC1=C(C=C2C(=C1)C(CCC2(C)C)(C)C)C3(CC3)C4=NC=C(C=C4)C(=O)O | ||
化学名称 | |||
分子式 | C24H29NO2 | 分子量 | 363.49 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | LG100268 is a potent and selective retinoid X receptor (RXR) agonist (EC50 = 4 nM). Displays >1000-fold selectivity for RXR over RAR. Activates RXR homodimers to induce transcriptional activation. Induces tissue transglutaminase (TGase) activity in HL-60 human promyelocytic leukemia cell line. Also activates RXR/PPARγ heterodimers. |
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