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CD1530 结构式

CD1530

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货号 :BCP28865CAS号 :107430-66-0纯度:98%
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  • 基本信息与产品描述
CAS号 107430-66-0 货号 BCP28865
中文名 CD1530
英文名 CD1530
中文别名
英文别名 CD 1530; CD-1530;
SMILES C1C2CC3CC1CC(C2)(C3)C4=C(C=C5C=CC(=CC5=C4)C6=CC=C(C=C6)C(=O)O)O
化学名称
分子式 C27H26O3 分子量 398.49
纯度 98% 配送 惯例下常温包邮
产品描述 CD1530 is a potent and selective retinoic acid receptor(RAR) agonist with Ki values of 150, 1500 and 2750 nM for RARγ, RARβ and RARα receptors respectively. It was also a potent CYP26A1 inhibitor as ketoconazole with an IC50 value of 530 nM. It inhibited excessive ROS production in tongue epithelial cells in vitro. It demonstrates transcriptional activity at RARγ with an AC50 value of 1.8 nM. It has been shown to preserve human tendon stem cell characteristics, promote repair of injured skeletal muscle, and in combination with bexarotene to inhibit oral carcinogenesis.
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